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Coronavirus COVID-19 Pandemic

Aleh said:
... neither article you linked provides either number. As such, you appear to be essentially pulling it out of your ass.
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Gee, what's this infografic, from the first link?

infographic-vaccine-development-1200x1850.png




No, I'm no expert. But, it's insanely obvious they're pushing HARD. That is always risky.
 
MadGreenSon said:
It has already been laid out for you how it's not what you think. Did you not read that or do you just prefer pessimism?
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I read it.

Given you didn't look at what I put up, I guess I shoulden't have.


I'll say it again. Not an expert. I just think you're wrong. 'Talking out your ass', was it?



Don't bother to try to convince me. I'm not really interested. Your anger tells me everything I need to know about you.
 
This chart is a little out of date and mostly covers the old-fashioned way of making a vaccine rather than the more modern mRNA techniques. Also, the numbers are suspect.

Discovery is a bit of a crapshoot, just digging deep into literature and theory to find all approaches the researchers think might possibly work. Most aren't ever a serious probability and will get internally eliminated before you ever hear about them. If anything, this chart could literally show 1,000,000+ options for this stage as some of the initial narrowing of things down is done automatically by computer with humans being more involved with some of the more promising options.

Preclinical is also messing around in the lab and you are unlikely to hear about that as well, unless we are talking about a novel approach such as mRNA.

Most vaccines' fail Phase 1 not because they are harmful, but because they don't appear to do anything or the trial is inconclusive. The same is true with Phase 2.

While a few vaccines are suspect, both of the approved ones in the US are solid products that have been well-reviewed and I'd be entirely confident in taking.
 
Simonbob said:
I read it.

Given you didn't look at what I put up, I guess I shoulden't have.


I'll say it again. Not an expert. I just think you're wrong. 'Talking out your ass', was it?



Don't bother to try to convince me. I'm not really interested. Your anger tells me everything I need to know about you.
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I'm not angry. I'm not even annoyed. It's just, the vaccine is a variation on one they've been working on for most of the 21st century thus far. Your infographic was very straightforward, most of that work has been ongoing for about fifteen years.
 
MadGreenSon said:
I'm not angry. I'm not even annoyed. It's just, the vaccine is a variation on one they've been working on for most of the 21st century thus far. Your infographic was very straightforward, most of that work has been ongoing for about fifteen years.
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The tone sounded very agressive. Enough to piss me off in return.


I came very close to saying something like "You sound like a fundamentalist being questioned about why their faith is wrong."


Ok. That's more understandable. There'd still have to be corners cut, and you told me of one in your rant. So, yes, I'm less worried about it, but I still think it's not as safe as something less rushed.



A while ago, I was working in a factory, and a guy under time pressure, who'd done well for years, cut his fingers off. It made an impression on me. So, now I worry a little more about such things.
 
The thing I don't get is that your own infographic goes from 20 in Pre-Clinical to 10 in the "is it safe" phase of Clinical. That's 50%. Which means even if it was accurate, it's completely disingenuous to use the 99% failure rate as justification for safety concerns. Efficacy concerns maybe, but we know it's effective.
 
Simonbob said:
The tone sounded very agressive. Enough to piss me off in return.


I came very close to saying something like "You sound like a fundamentalist being questioned about why their faith is wrong."


Ok. That's more understandable. There'd still have to be corners cut, and you told me of one in your rant. So, yes, I'm less worried about it, but I still think it's not as safe as something less rushed.



A while ago, I was working in a factory, and a guy under time pressure, who'd done well for years, cut his fingers off. It made an impression on me. So, now I worry a little more about such things.
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I'm not too worried about it personally. Everyone I care about who's likely to die has already died. I'm too poor to get the vaccine very soon, so I'll know one way or the other before I get it and I am not relaxing vigilance until six months after I get it anyway.
 
MadGreenSon said:
I'm not too worried about it personally. Everyone I care about who's likely to die has already died. I'm too poor to get the vaccine very soon, so I'll know one way or the other before I get it and I am not relaxing vigilance until six months after I get it anyway.
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My folks are 80, so in the danger zone, but, well, Mom's gone, mentally, and Dad doesn't care. He'd rather die with his wits.


I'll wait a few years, and see what happens.
 
Aleh said:
So, some sick fuck of an antivaxxer in Wisconsin just deliberately destroyed 500+ doses of the Moderna vaccine.

Just... ugh.
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Aleh said:
The bastard has been arrested, on...

He is also even more of a bastard than I previously thought, as he attempted to hide the destruction so that people would actually get the now-ineffective injections. I shit you not.
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We have new details thanks to released court documents. He is, apparently, an avid conspiracy theorist of the "Doomsday Prepper" variety... and, of course, included antivaccine screeds in that.

Associated Press said:
A Wisconsin pharmacist convinced the world was "crashing down" told police he tried to ruin hundreds of doses of coronavirus vaccine because he believed the shots would mutate people's DNA, according to court documents released Monday.
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Fox News said:
According to an affidavit his wife filed on Dec. 30 -- the same day Brandenburg was arrested in the vaccine tampering -- he had stopped at her house on Dec. 6 and dropped off a water purifier and two 30-day supplies of food, telling her that the world was "crashing down" and she was in denial. He said the government was planning cyberattacks and was going to shut down the power grid.

She added that he was storing food in bulk along with guns in rental units and she no longer felt safe around him. A court commissioner on Monday found that Brandenburg's children were in imminent danger and temporarily prohibited them from staying with him.
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Let me add that the idea that an mRNA vaccine like this can mutate DNA is biologically implausible. It makes no sense, and, if somehow true, would utterly upend our fundamental understanding of how cells work.
 
Aleh said:
Yes. The COVID vaccines are many things, but they were very much not developed in a basement lab by a one-armed doctor named Connors.
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The "m" in mRNA is for messenger, and angels means messenger, therefore every shot contains an angel.

Fight crazy with superior crazy.​
 
Well, I had my 1st shot yesterday and felt like crap for most of today (37.6C, flu-like symptoms), better now. 2nd one in 3 weeks.
 
thomask2 said:
Because of the Covid I can't meet with my family and friends and gather together. It makes me feel really frustrated. We really love play table games, cook together, drink coffee, and watch soap operas in my parents' house. Really miss my old reality.
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Believe me, you are not the only one to think that way.
 
Well my mother was exposed because one of the teachers she works with came in fucking sick. Fuck the New York educational system, fuck it so hard. They should have been exclusively remote at elementary school level but I guess the parents can't live without their fucking glorified daycare.
 
Are you a parent? Because a lot of people actually do have to earn a living in places where you can't take children, or else starve themselves and said children.
 
OverMaster said:
Are you a parent? Because a lot of people actually do have to earn a living in places where you can't take children, or else starve themselves and said children.
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This is no excuse for endangering the lives of others. A sick teacher will potentially expose other teachers, children and parents.
 
Doing new tasks that can be done at home is hella relaxing in this kind of time. Reading physical books, watch films I usually don't, finish my games, redecorate the house interiors, and learning more cooking recipes helped take my mind off large-scale things.
 
Antivaxxers just gathered at the entrance to a major COVID vaccination site in LA -- the center of America's currently-largest COVID outbreak -- protesting the vaccines with enough vitriol that the place had to be shut down for an hour or so... much to the frustration of the people who were waiting for the life-saving shot.

I... genuinely lack words.

Edit: Apparently, the specific trigger for the place needing to be shut down was the antivaxxers attempting to breach into the area where vaccines were actually being administered, presumably so they could harass and harangue the people actually giving the shots (and/or the people *getting* them).
 
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Aleh said:
Antivaxxers just gathered at the entrance to a major COVID vaccination site in LA -- the center of America's currently-largest COVID outbreak -- protesting the vaccines with enough vitriol that the place had to be shut down for an hour or so... much to the frustration of the people who were waiting for the life-saving shot.

I... genuinely lack words.

Edit: Apparently, the specific trigger for the place needing to be shut down was the antivaxxers attempting to breach into the area where vaccines were actually being administered, presumably so they could harass and harangue the people actually giving the shots (and/or the people *getting* them).
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It's madness.

My inner ITG wants to post that the protesters should also be given shots (of the 9mm variety), but honestly they're not in their right minds and it's uncool to execute people who are effectively insane.
 
So as of about.... ten minutes or so ago, Western Australia has gone into lockdown. Apparently there is going to be more details on the news tonight so I don't know what is going to happen yet.

My job classes me as an essential worker which I am both glad and annoyed at. :V
 
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